Method validation for measurement of hair nicotine level in nonsmokers.

This publication co-authored by USC Institute for Global Health Director Jonathan Samet address the growing worldwide burden of exposure to secondhand smoke (SHS) would be facilitated by sensitive and accurate methods for assessing SHS exposure. Hair provides a readily available matrix for assessing biomarkers of typical SHS exposure. We developed and applied an optimized analytical method using an isotope dilution gas chromatography-mass spectrometry (GC/MS) for hair nicotine measurement.

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Authors: Kim SR, Wipfli H, Avila-Tang E, Samet JM, Breysse PN
Published By: Biomedical Chromatography
Date: March 23, 2009
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