From evidence to action: challenges for the Brazilian Unified National Health System in offering pre-exposure prophylaxis (PrEP) for HIV to persons with the greatest vulnerability

Pre-exposure sexual prophylaxis (PrEP) has been considered strategic and promising in controlling the HIV epidemic globally. However, it is necessary to transpose the knowledge accumulated by efficacy and demonstration studies to the reality of the services and populations most vulnerable to infection, in order to reach a wide coverage of PrEP. It is proposed to reflect on this challenge by focusing on two dimensions: the users of prophylaxis, with emphasis on contexts of practices and potential exposure to HIV; the comparative advantages of prophylaxis in relation to the other methods and the challenges for a safe and protective use; and services, taking into account the organizational principles that could make the offer and the incorporation of PrEP more successful in the context of combined prevention strategies. [Translated from Portuguese]

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Authors: Eliana Miura Zucchi, Alexandre Grangeiro, Dulce Ferraz, Thiago Félix Pinheiro, Tatianna Alencar, Laura Ferguson, Denize Lotufo Estevam, Rosemeire Munhoz, Equipe do Estudo Combina!
Published By: Cadernos de Saúde Pública 
Date: May 2, 2018
Publication Link: https://www.scielosp.org/pdf/csp/2018.v34n7/e00206617/pt