COVID-19 exposed the fundamental weaknesses in pandemic preparedness and response at national and global levels in unprecedented ways. On Feb. 8, IIGH brought together key players engaged in these negotiations to discuss crucial issues in achieving a globally coordinated and effective instrument on pandemic prevention, preparedness and response. The panel explored the history, purpose, content and current state of play concerning the pandemic agreement, with special attention to addressing inequalities, and the legal, structural and political issues to be addressed moving forward.